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It�is�approved�as�a�secondary�treatment�for�treating�familial�adenomatous�polyposis�among�patients. The investigation concluded that, although slower acting, SAM-e supplements joint health are as good as Celebrex for pain of osteoarthritis in the knee-related. omega-3s can not only inhibit COX-2, but in addition slow the rate of joint degradation that produces arthritic pain. Celebrex is now the only cox-2 inhibitor available, since Vioxx and Bextra were recalled.

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